Purpose Urological manifestations of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are uncommon and management strategies are unclear. This scoping review identifies the range of these manifestations and describes management and prevention strategies. Methodology MEDLINE and Embase were searched for comparative studies, case reports and series, review articles, and clinical guidelines addressing the nature, outcomes, management, and prevention strategies of urological manifestations of SJS/TEN. Two reviewers independently screened 307 abstracts. Results Eighty-four articles were included in the study. Urological manifestations of SJS/TEN included cutaneous genital lesions, mucositis and erosion, clot retention, phimosis, and balanitis. Urethral sequelae were present in 5.7-9.6% of patients with SJS/TEN and included urethritis, stricture, and synechiae. Outcomes include re-epithelialisation, secondary infection, urinary and sexual dysfunction, and septic shock. Patients with urological manifestations of SJS/TEN should be managed in a tertiary centre with multidisciplinary involvement. Cross-sectional imaging and monitoring of renal function should be performed to detect upper urinary tract manifestations. Indwelling catheterisation is recommended to manage and prevent urethral strictures. Regular preputial retraction in uncircumcised male patients can prevent adhesional phimosis. External urethral orifice adhesions should be lysed with paraffin ointment. Patients should be reviewed for up to 12 months to monitor for long-term manifestations. Conclusion Urological manifestations must be considered in patients with SJS/TEN. This review serves as a resource to inform care practices for these patients.