Talk Description
Institution: Blacktown Hospital - NSW, Australia
PURPOSE
Bladder cancer prognosis and management rely on accurate pathological staging, with detrusor muscle presence in the specimen representing an important aspect of a quality TURBT. En bloc resection has been proposed to provide a better specimen for pathological examination and reduce tumour seeding but is not commonly performed. This study assessed the feasibility and pathological outcomes of en bloc TURBT for appropriate tumours at our centre.
METHODOLOGY
We performed a prospective, nonrandomised study that recruited patients diagnosed with bladder cancer in one tertiary public teaching hospital in Sydney, Australia. Inclusion criteria were: (1) Tumour size <5cm, (2) three or fewer lesions, (3) no radiological/clinical concerns of muscle/ureteric involvement, and (4) deemed appropriate by the supervising consultant at time of procedure. The primary outcome was the Prescence of detrusor muscle at final histology. Secondary outcomes include perioperative complications.
RESULTS
In 15 patients who underwent en-block TURBT between February and June 2024, 24 lesions were removed. Mean tumour size was 2.47cm 1.25 (mean std). 11/15 (n=73%) specimens resected contained detrusor muscle. Two patients required an indwelling urethral catheter for 1 week postoperatively due to extraperitoneal bladder perforation. A significant barrier encountered was the difficult in extracting the specimen with the use of large stone crushing forceps, required in 4 cases.
CONCLUSION
En-bloc TURBT is feasible, with an appropriate learning curve and excellent pathological outcomes for suitable lesions. Larger sample sizes are required to compare its benefits to re-resection TURBT histopathology.
Presenters
Authors
Authors
Dr Oliver Best - , Dr David Armany - , Dr Lequang Vo - , Prof Henry Woo -