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RACS ASC 2025
Natural History of LUTS Following TURP: A Prospective Observational Study
Verbal Presentation
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Verbal Presentation

2:00 pm

03 May 2025

Meeting Room C3.4

ADVANCES IN AUSTRALASIAN UROLOGY

Disciplines

Urology Surgery

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Presentation Description

Institution: Austin Health - Victoria, Australia

Purpose: TURP is the most common surgical intervention to address bladder outlet obstruction. Patients are counselled to expect an exacerbation of irritative symptoms post-operatively such as frequency, urgency and nocturia. This study aims to investigate the temporal changes in LUTS following TURP, as assessed by fortnightly completion of the International Prostate Symptom Score (IPSS). Methods: Forty-two men undergoing TURP were prospectively enrolled. Patients completed the IPSS pre-operatively and at 2, 4, 6 & 8 weeks post-operatively. Age, BMI, prior TURP, resected prostate mass, histology, analgesia, UTIs and unplanned readmissions were also collected. Results: Irritative symptoms saw an immediate improvement at 2-weeks compared to baseline which was sustained until final follow up. Quality of life improved by 54% and was moderately correlated with frequency (r=0.68), weak stream (r=0.63) and nocturia (r=0.61). Both resected prostate mass and age displayed poor correlation with IPSS symptoms (r=-0.09 to -0.36 and 0.01 to 0.22 respectively). Analgesia use decreased over time to 34%, 16%, 12%, and 8% at 2, 4, 6, and 8-weeks respectively. Antibiotics for UTI were given in 14% of patients, whilst 5% required re-admission due to clot retention. Conclusion: Contrary to common clinician expectations, irritative LUTS did not worsen in the initial post-operative period. Quality of life was correlated with a mixture of irritative and obstructive symptoms. These findings now quantify expected rates of improvement post-operatively and allow for the potential of tailored interventions such as pharmacotherapy to enhance patient experience and outcomes.
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Authors

Dr Alice Thomson - , Dr Arthur Yim - , Dr Kirby Qin - , Prof Damien Bolton - , Mr Peter Liodakis -