ePoster
Talk Description
Institution: Princess Alexandra Hospital Upper Gastrointestinal and Soft Tissue unit - Queensland, Australia
Purpose: Textbook surgical outcomes (TO) are composite measures, beyond peri-operative mortality and pathological parameters, developed to compare ideal outcomes post complex oncologic resections. For patients with retroperitoneal sarcomas (RPS), en-bloc resection with macroscopically negative margins remains the only potentially curative treatment. The aim of this study was to define TO for RPS resections, and to assess its impact on disease-free (DFS) and disease-specific survival (DSS).
Methodology: Data from the Queensland Oncology Repository was used to perform a retrospective review of all patients who underwent resection for primary RPS in Queensland between 2012 to 2022. TO was defined as: en-bloc resection with involved contiguous organs; macroscopically negative margins; no unplanned ICU admission, no clavien-dindo III or greater complication; hospital stay <75th percentile, no 30 day re-admission and no 90-day mortality.
Results: TO was achieved in 78 (54%) of the 114 patients who had a resection. Factors associated with TO were: pre-operative diagnosis of sarcoma (p<0.01); well-differentiated tumours (p<0.01); resection of up to two contiguous organs (p<0.01) and there was a trend towards patients treated at high-volume specialist sarcoma centres (p=0.07). The most common reason for failure to achieve TO were; prolonged length of stay (22%) and peri-operative readmission (17%). Achieving a TO was associated with a greater five-year DFS survival (62% vs. 54%, p<0.05) and DSS (80% vs. 68%, p<0.05).
Conclusion: TO provides a measure of the quality of RPS resection across multiple health services, with higher TO rates associated with decreased recurrence and improved disease related survival.
Presenters
Authors
Authors
Dr Skyle Murphy - , Dr Christopher Allan - , Prof Andrew Barbour - , Victoria Donoghue - , Prof Mark Smithers -