De Garengeot hernia is a rare type of femoral hernia in which the appendix is contained within the hernial sac. Due to its rarity, there is limited evidence regarding its optimal surgical approach. Twenty‑five reports of repair using the laparoscopic transabdominal preperitoneal (TAPP) technique have been identified; however, there is a lack of consensus pertaining to preoperative diagnosis and whether concurrent appendicectomy is performed. In addition, there is debate over the use of a covering mesh. A 34‑year‑old woman presented with a 5‑week history of pain in the right groin. On examination, an irreducible, tender mass was identified in the groin. A computed tomography scan illustrated a right femoral hernia containing the appendix, demonstrating features of acute uncomplicated appendicitis. The patient underwent laparoscopic TAPP repair with mesh plus appendicectomy and made an uncomplicated recovery. Here, we present laparoscopic TAPP repair with mesh plus appendicectomy as a safe and feasible surgical method for managing De Garengeot hernia with concurrent uncomplicated appendicitis.