Purpose Currently in South Australia, patients undergoing minimally invasive parathyroidectomy (MIP) are routinely admitted for overnight observation due to concerns regarding postoperative complications such as bleeding and hypocalcaemia. In recent years, there has been an increasing trend in the number of patients undergoing MIP as day surgery in other institutions, with many centres demonstrating it is safe and feasible. Additionally, with increasing hospital bed pressures, MIPs are often cancelled to facilitate more urgent cases. We aim to assess our complication rates after MIP to see if it is feasible to implement in our setting, and to use this data to create a day procedure protocol. Methodology A multicentre retrospective observational cohort study was undertaken across two metropolitan tertiary hospital networks in South Australia, between June 2023 and June 2025. All patients undergoing MIP for primary hyperparathyroidism were included. Patient demographics, imaging localisation, blood results, histopathology, operative findings and clinical outcome data were extracted from patient records and assessed for complications. Results Ninety-six patients were identified who underwent a minimally invasive parathyroidectomy for a preoperatively localised parathyroid adenoma. One patient had a postoperative bleed, one patient had hypocalcaemia requiring oral calcium replacement, one patient had hyperkalaemia, one patient had an allergic reaction to an anaesthetic agent. The remaining ninety-two patients (96%) had an unremarkable postoperative recovery and were discharged home the following day without complication. No patients were readmitted due to complications in the immediate postoperative period or subsequent 30 days. Conclusion Complication rates in our population appeared comparable to national standards and published literature. As a result, day case MIP appears to be feasible and safe for management of primary hyperparathyroidism in the Australian setting for selected patient populations with an unremarkable intraoperative course.