ePoster
Presentation Description
Institution: Peter MacCallum Cancer Centre - VIC, Australia
Introduction: Delayed gastric conduit emptying (DGCE) is a common functional complication following oesophagectomy, significantly impairing quality of life. Despite its clinical burden, standardised management protocols are lacking, and treatment approaches often rely on individual surgeon preference. This review evaluates evidence on procedural interventions for DGCE to inform clinical decision-making.
Methods: A systematic review was conducted across five databases, identifying 26 studies on DGCE interventions. Studies were assessed for quality using the Newcastle-Ottawa Scale, emphasising inclusion criteria focusing on procedural efficacy and outcome reporting.
Results: Twenty-six studies encompassing diverse treatment modalities were included. Endoscopic approaches such as botulinum toxin injection and balloon dilation emerged as preferred first-line interventions with success rates ranging from 50.0-100.0%. A hybrid approach combining both modalities demonstrated enhanced efficacy and lower recurrence, with success rates reaching 100.0%. Gastric peroral endoscopic myotomy (G-POEM) showed promise for treatment-resistant DGCE, with experienced centres reporting success in 77.2% of refractory cases. Surgical options for gastric conduit revision were reserved for cases of DGCE with structural abnormalities, though associated with higher risks and complications. Significant heterogeneity in outcome definitions and reporting limited comparability between studies.
Conclusion: This comprehensive evaluation provides valuable insights to assist clinicians in navigating current management strategies for DGCE. High-quality comparative studies are essential to refine treatment protocols and improve long-term patient outcomes.
Presenters
Authors
Authors
Dr Jonathan Sivakumar - , Dr Feras Alnimri - , A/Prof Cuong Duong -