Audit of Venous Thromboembolism Prophylaxis Prescribing in a Level I Trauma Centre JULIA SHEARER*, CORMAC MULHALL, JENI THOMAS ROYAL PERTH HOSPITAL, PERTH, WA. Purpose: Venous thromboembolism (VTE) is a leading cause of preventable morbidity and mortality in trauma. Prescribing chemical VTE prophylaxis (VTEp) is often complex due to contraindications such as solid organ injury, intracranial haemorrhage, epidural haematoma, active bleeding, or planned regional anaesthesia and surgery. Guidelines recommend initiating VTEp as early as possible when safe. This study aims to audit prescribing of VTEp in a level I trauma centre, and identify areas for improvement. Methods: A retrospective audit was conducted of patients admitted to the State Major Trauma Unit over a one-month period. Data was collected from digital medical records on demographics, contraindications, VTEp prescribing, and VTE outcomes. 178 records were accessed, with 6 excluded. Results: Of 172 patients, 153 (89%) had chemical VTEp charted. Median time from admission to first dose of VTEp is 1 day, including those with contraindications. Median time for patients with high grade solid organ injury is 2 days. There were 0 adverse bleeding events, and 1 PE which was present on admission CT. 26 cases were identified with unnecessary delay to VTEp prescribing. Conclusion: VTEp prescribing in our level I trauma centre is done well, with the majority of patients receiving VTEp early in their admission. It is prescribed early in high grade solid organ injury with 0 adverse bleeding events. Opportunities remain to reduce unnecessary delays and further optimise prescribing practices.