Purpose: This study aims to evaluate laparoscopic cholecystectomy (LC) and laparoscopic common bile duct exploration (LCBDE) as standard treatment options for cholelithiasis and choledocholithiasis in a regional healthcare setting. It focuses on identifying the types of complications encountered and their management strategies. Methodology: In this six-month retrospective study, 235 patients underwent LC in Cairns Hospital from January to June 2024. Data were collected on intraoperative and postoperative complications, with a subgroup analysis specifically examining LCBDE and associated complications. Results: Among the 235 cases, 38.7% were for acute cholecystitis, with 24.6% involving patients over 65 years. The average operation time was 101 minutes. Key intraoperative complications included liver injury (3.4%), bile leak (2.6%), and haemorrhage (0.4%). Conversion to open surgery was required in 1.3% of cases, and subtotal cholecystectomy was performed in 2.6%, generally due to obscure anatomy from inflammation. Postoperative complications included retained bile stones (2.6%), surgical site infections (0.9%), and haemorrhage (0.4%), with one death recorded (0.4%). Minimally invasive methods managed 71.4% of postoperative complications, including 3 laparoscopic re-operations and 10 endoscopic sphincterotomies. 19 cases (8.1%) required LCBDE, with only two cases of liver tear related to retraction. The duct clearance rate was 94.1%. Conclusion Our findings demonstrate a high success rate and low complication profile with LC and LCBDE, highlighting that LCBDE can be safely and effectively performed in a regional centre by general surgeons with appropriate laparoscopic expertise.