Purpose To improve outcomes for children with uncomplicated appendicitis at two Australian tertiary pediatric hospitals. Method The American College of Surgeons National Surgical Quality Improvement Program – Pediatric (NSQIP-P) reports are extrapolated from case reviews with a 30-day post-operative follow up. The reports, from 2020 to 2022, flagged our uncomplicated appendicectomy post-operative length of stay as ‘needing improvement’ with a median of 24hrs (n=152). Further investigations found that discharge was delayed by post-operative administration of intravenous fluids, antibiotics and opioids. A quality improvement project was initiated using Clinical Redesign Methodology. After process mapping and a root cause analysis, an Uncomplicated Appendicitis Guideline was created. The Guideline allowed for a nurse-led discharge criteria to be applied after 6 hours of post-operative recovery. A comprehensive discharge information sheet was provided to equip parents/carers to care for their child at home. Results Post project implementation in 2023, there were no increased post-operative readmissions (n=891). There was a slight increase in post-operative Emergency Department presentations noted at both sites, from a median of 7 annual presentations to 10 annual presentations. The median length of stay was reduced by 7hrs with no negative feedback from parents (n=10). Parents who had received the discharge information sheet were found to be better informed about their child’s care. Staff in focus groups highlighted a greater autonomy in post-operative care (n=5). Conclusion Pediatric patients with uncomplicated appendicitis can be safely discharged from 6 hours post-operatively with adequate discharge information.