ePoster
Presentation Description
Institution: Western Sydney University - NSW, Australia
Background/Purpose:
Management of burns and and complex wounds has evolved beyond survival to prioritise both improving functional and aesthetic outcomes. Innovations in tissue engineering, offer a promising future in reconstruction. By utilizing innovative natural or synthetic biomaterials, bioinks embedded with cells, and therapeutic agents, 3D bioprinting provides a customizable approach to wound healing and tissue regeneration.
Methods:
This review examines the principles of 3D bioprinting, focusing on the use of bioinks comprising cellular and biomaterial components. The process involves layer-by-layer deposition of cells, extracellular matrix analogs, and growth factors to create skin constructs with structural and functional fidelity. Key advancements in bioprinting technologies, such as inkjet, extrusion, and laser-assisted systems were explored.
Results:
15 Studies demonstrated that bioink composition significantly influences cell viability, proliferation, and wound healing success. University of Western Australia and Curtin university are currently developing technologies in 3D skin bioprinting. A critical limitation identified was the challenge of generating an adequate quantity of cells for clinical-grade bioprinted constructs. Many studies reported enhanced wound healing outcomes, reducing scarring, and promising tissue integration.
Conclusion:
3D skin bioprinting has emerged as a revolutionary tool in burn and trauma care, capable of producing biocompatible skin substitutes in a sustainable fashion. With continued innovation, 3D bioprinting is poised to transform the landscape of wound reconstruction and regenerative medicine.
Presenters
Authors
Authors
Dr Khadijah Younus - , Dr. Sarah Huang -